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1.
Arch. pediatr. Urug ; 94(2): e308, 2023. ilus, tab
Article in Spanish | LILACS, UY-BNMED, BNUY | ID: biblio-1520107

ABSTRACT

El acné una de las enfermedades dermatológicas crónicas más frecuentes, siendo la adolescencia donde se observa su mayor incidencia y prevalencia. Constituye un motivo de consulta frecuente y a pesar de que su abordaje inicial es de resorte del pediatra, dependiendo de la evolución y los tipos de acné requieren la derivación y tratamiento con dermatólogo. Es una enfermedad cutánea, de carácter inflamatorio y que involucra la unidad pilosebácea. Su etiología es multifactorial y el diagnóstico es clínico al constatar las lesiones típicas. Teniendo en cuenta la importancia de la imagen corporal en esta etapa de la vida y el impacto de esta en la calidad de vida de los adolescentes, es imprescindible el reconocimiento precoz y tratamiento inicial por parte del pediatra. Existen posibilidades terapéuticas cada vez más novedosas, exigiendo a los profesionales de salud estar actualizados. Esta revisión pretende mostrar una puesta al día de la temática y ofrecer información actualizada sobre los tratamientos disponibles a nivel local.


Acne is one of the most common chronic dermatological diseases and it is primarily observed in adolescents. It is one of the causes of frequent consultation, and despite the fact that Its initial detection and approach is that of the pediatrician, depending on the evolution and the types of acne, referral and treatment by a dermatologist will be required. It is a skin disease, inflammatory in nature and involving the pilosebaceous unit. It has a multifactorial etiology and it requires clinical diagnosis when typical lesions are found. Considering importance of adolescents' image at this stage and the impact on their quality of life, early detection and treatment by the pediatrician are essential. There are increasing new therapeutic possibilities, which require health professionals to be updated. This review aims at showing an update of the subject and at providing updated information regarding the available treatments locally.


A acne é uma das doenças dermatológicas crônicas mais comuns, sendo a adolescência onde observase sua maior incidência e prevalência. Constitui motivo de consulta frequente e apesar de sua abordagem inicial é a do pediatra, dependendo da evolução e dos tipos de acne que necessitam de tratamento e encaminhamento feito por um dermatologista. É uma doença cutânea, de natureza inflamatória e que envolve a unidade pilossebácea. Sua etiologia é multifatorial e o diagnóstico é clínico quando são encontradas lesões típicas. Tendo em conta a importância da imagem corporal nesta fase da vida e o impacto dela na qualidade de vida dos adolescentes, o reconhecimento inicial pelo pediatra e o tratamento precoces são essenciais. Existem cada vez mais novas possibilidades terapêuticas, exigindo que os profissionais de saúde estejam atualizados. Este papertem como objetivo mostrar uma atualização do assunto e fornecer informação atualizada sobre os tratamentos disponíveis a nível local.


Subject(s)
Humans , Adolescent , Acne Vulgaris/drug therapy , Acne Vulgaris/diagnosis
2.
In. Alonso Texeira Nuñez, Felicita; Ferreiro Paltre, Patricia B; González Brandi, Nancy Beatriz. Adolescencias: una mirada integral. Montevideo, Bibliomédica, c2022. p.141-150, tab.
Monography in Spanish | LILACS, UY-BNMED, BNUY | ID: biblio-1416897
3.
Rev. cuba. enferm ; 37(1): e3530, 2021. graf
Article in Spanish | LILACS, BDENF, CUMED | ID: biblio-1341373

ABSTRACT

Introducción: Algunos profesionales tienen dificultades para hacer la detección correcta de los signos y síntomas y para prescribir el tratamiento adecuado del acné II, que puede conducir a un tratamiento estético insatisfactorio. Por lo tanto, es necesario desarrollar tecnología educativa, por ejemplo, una aplicación. Objetivo: Desarrollar una aplicación multimedia en una plataforma móvil para el diagnóstico, prevención y tratamiento estético del acné grado II. Métodos: Las fases de desarrollo de la estructura de la aplicación fueron: Fase 1 - "Concepción: identificación de las necesidades del desarrollo de la aplicación". Fase 2 - "Elaboración del prototipo de aplicación": esta fase incluyó la revisión integradora de la literatura en las principales bases de datos. Fase 3- "Creación de la aplicación": esta fase consistió en desarrollar el algoritmo, estructurar la base de datos y desarrollar el software; Fase 4- "Transición": se realizaron las pruebas de funcionalidad de la aplicación. Resultados: La aplicación móvil consta de 10 pantallas descriptivas y 4 pantallas con videos explicativos, el cual se registró en el Instituto Nacional de Propiedad Industrial (Ministerio de Desarrollo, Industria y Comercio Exterior) con el número de protocolo: BR: 51 2018 0001475 y está disponible de forma gratuita en línea en Google Play Store con el nombre de Face Care. Conclusión: El estudio permitió describir las etapas de planificación y desarrollo de una aplicación multimedia en una plataforma móvil para el diagnóstico, prevención y tratamiento estético del acné grado II(AU)


Introduction: Some professionals have difficulties in correctly detecting signs and symptoms of acne II, as well as in prescribing the appropriate treatment for the condition, a fact that can lead to unsatisfactory cosmetic treatment. Therefore, it is necessary to develop educational technology; for example, an application. Objective: To develop a multimedia application on a mobile platform for diagnosis, prevention and cosmetic treatment of grade II acne. Methods: The application structure was developed in four phases: conception (identification of the application development needs), development of the application prototype (which included the integrative review of the literature from the main databases), creation of the application (which consisted in developing the algorithm, structuring the database and developing the software), and transition (during which the application's functionality tests were carried out). Results: The mobile application consists of ten descriptive screens and four screens with explanatory videos. It was registered within the National Institute of Industrial Property (Ministry of Development, Industry and Foreign Trade), with the protocol number BR: 51 2018 0001475. It is available online, for free, on the Google Play Store, under the name Face Care. Conclusion: This study allowed to describe the planning and development stages of a multimedia application on a mobile platform for the diagnosis, prevention and cosmetic treatment of grade II acne(AU)


Subject(s)
Humans , Software/trends , Acne Vulgaris/diagnosis , Mobile Applications , Audiovisual Aids , Acne Vulgaris/therapy
4.
Rev. medica electron ; 41(2): 323-332, mar.-abr. 2019. tab
Article in Spanish | LILACS, CUMED | ID: biblio-1004270

ABSTRACT

RESUMEN Introducción: el acné es una enfermedad multifactorial que afecta en estructura y función a la unidad pilosebácea. Se presenta en los adolescentes y se padece mundialmente. En los casos más severos, puede involucrar al grupo familiar en su esfera afectiva y económica. La terapia láser de baja potencia se ha empleado como opción de procedimiento médico alternativo para el tratamiento de esta enfermedad; por su acción antibacteriana, antiedematosa y estimulante del sistema inmunitario. Objetivo: determinar el comportamiento del acné vulgar en pacientes con terapia láser de baja potencia. Materiales y métodos: se realizó un estudio descriptivo, prospectivo, en pacientes con formas clínicas leves y moderadas de acné vulgar que acudieron a la consulta de Dermatología del Hospital Universitario Comandante "Faustino Pérez Hernández", provincia Matanzas, entre junio del 2015 a junio del 2016. Se estudiaron las variables: edad, sexo, color de la piel, nivel de escolaridad, clasificación del acné, número de lesiones inflamatorias por hemicara, su tamaño, respuesta al tratamiento y grado de satisfacción. Se procesaron en el paquete estadístico SPSS para Windows, versión 16.0. Resultados: la mayor frecuencia de presentación fue de 18-25 años, sexo femenino y raza blanca. Respuesta satisfactoria independiente a su clasificación, con 15 sesiones, dos veces por semana. Conclusiones: el láser de baja potencia mejora y acorta el tiempo de evolución del acné vulgar.


ABSTRACT Introduction: acne is a multifactor disease that affects the structure and function of the pilosebaceous unit. It is a global condition that starts during adolescence. It can involve the family in its affective and economic sphere in the most severe cases. Low-power laser therapy is used as an alternative medical procedure for the treatment of this disease due to its antibacterial, antiedematous and immune-stimulant action. Objective: to determine the behavior of acne vulgar in patients under low potency laser therapy. Materials and methods: a descriptive, prospective study was carried out in patients suffering mild and moderated clinical forms of acne vulgaris who assisted the Dermatology consultation of the University Clinico-surgical Hospital "Faustino Perez Hernandez"¨, Matanzas province, from June 2015 to June 2016. The studied variables were age, sex, race, scholarship, acne classification, number of inflammatory lesions per hemiface, lesson size, answer to treatment and satisfaction level. Data were processed with the SPSS statistical package, 16.0 version for Windows. Results: the highest presentation frequency was in people aged 18-25 years, of the female sex and white race. The answer was satisfactory independently to classification with 15 sessions, twice a week. Conclusion: low potency laser improves and reduces acne vulgaris evolution time.


Subject(s)
Humans , Adolescent , Adult , Acne Vulgaris/diagnosis , Acne Vulgaris/prevention & control , Acne Vulgaris/radiotherapy , Low-Level Light Therapy/instrumentation , Epidemiology, Descriptive , Prospective Studies
5.
Evid. actual. práct. ambul ; 21(3): 89-91, oct. 2018. tab., ilus.
Article in Spanish | LILACS | ID: biblio-1016246

ABSTRACT

El acné es la enfermedad dermatológica más común de la adolescencia. Aunque casi todos los casos remiten alrededor de la tercera década de la vida, cuando este problema conlleva una carga emocional para el paciente se requiere indicar tratamiento. En esta actualización, los autores revisan los distintos grados de compromiso de esta patología, el tratami-ento y los niveles de evidencia que tiene cada uno de ellos, con el objetivo de facilitar a los médicos de atención primaria el manejo de los pacientes que presentan esta enfermedad. (AU)


Acne is the most common dermatological condition in adolescents. Even though almost all cases will resolve around the third decade of life, treatment is indicated when this health problem carries an emotional burden for the patient. In this update, the authors review the grades of involvement of the disease and the available treatments according to levels of evidence, with the aim of helping primary care physicians to manage the patients presenting this illness. (AU)


Subject(s)
Humans , Male , Female , Adolescent , Adult , Young Adult , Acne Vulgaris/therapy , Acne Conglobata/therapy , Anxiety , Self Concept , Skin Diseases/etiology , Testosterone/adverse effects , Cicatrix/prevention & control , Skin Diseases, Papulosquamous/therapy , Dermatitis, Seborrheic/diagnosis , Acne Vulgaris/diagnosis , Acne Vulgaris/pathology , Acne Vulgaris/psychology , Acne Vulgaris/drug therapy , Rosacea/diagnosis , Acne Conglobata/diagnosis , Folliculitis/diagnosis
6.
Porto Alegre; Universidade Federal do Rio Grande do Sul. Telessaúde; 2017. ilus.
Non-conventional in Portuguese | LILACS | ID: biblio-995629

ABSTRACT

Acne é a dermatose mais comum, acometendo cerca de 80% dos adolescentes e adultos jovens. É caracterizada por lesões não-inflamatórias (comedões abertos e/ou fechados) e por lesões inflamatórias (pápulas, pústulas, cistos ou nódulos) tipicamente localizados na face, pescoço, dorso, tórax e braços. A etiologia da acne vulgar resulta da associação dos seguintes fatores: hiperqueratinização e obstrução do infundíulo folicular, devido à descamação anormal do epitélio folicular; aumento da produção de sebo estimulada pelos andrógenos; colonização do folículo pelo Propionibacterium acnes, gerando inflamação. Esta guia apresenta informação que orienta a conduta para casos de acne no contexto da Atenção Primária à Saúde, incluindo: classificação da acne vulgar, Características da acne vulgar, Erupção acneiforme, Diagnóstico da acne vulgar, Tratamento - Orientações gerais, Tratamento - Medicamentos, Terapia tópica, Antibióticos sistêmicos, Terapia antiandrogênica, Acne na Gestante, Acompanhamento, Encaminhamento para serviço especializado.


Subject(s)
Humans , Acneiform Eruptions , Acne Vulgaris/diagnosis , Acne Vulgaris/therapy , Primary Health Care , Referral and Consultation , Tretinoin/therapeutic use , Benzoyl Peroxide/therapeutic use , Clindamycin/therapeutic use , Isotretinoin/therapeutic use , Erythromycin/therapeutic use , Adrenal Cortex Hormones/therapeutic use , Adapalene/therapeutic use
7.
Dermatol. argent ; 21(4): 304-307, 2015. ilus, graf
Article in Spanish | LILACS | ID: lil-784771

ABSTRACT

La cicatrización patológica es una complicación frecuente del acné que resulta del daño en la piel que se produce durante la curación de dicho proceso inflamatorio. Muchos pacientes desarrollarán cicatrices a pesar de un tratamiento oportuno y adecuado. A grandes rasgos se consideran dos tipos de cicatrización patológica: excesiva (cicatrices hipertróficas y queloides) e insuficiente (cicatrices atróficas). Estas últimas se ven en el 80-90% delos casos y se subclasifican en pica hielo, ondulada y en caja. Múltiples tratamientos se usan para eliminar las cicatrices del acné. A menudo, una combinación de varias técnicases necesaria para un tratamiento efectivo. La técnica CROSS es una modalidad terapéutica segura, eficaz y rentable en el tratamiento de las cicatrices pica hielo sin complicaciones significativas.


Pathological scarringis a common complication of acne that results from the skin damagethat occurs during the healing of this inflammatory process. Many patients develop scarringdespite a timely and appropriate treatment. Roughly two types of scarring are considered:excessive (hypertrophic scars and keloids) and insufficient (atrophic scars). The latter are seen in 80-90% of cases and are subclassified into ice pick, rolling and box car. Multiple treatments are used to remove acne scars. Often a combination of several techniquesis necessary for an effective treatment. The CROSS technique is a safe, effective andprofitable therapeutic modality for the treatment of ice pick scars without significant complications.


Subject(s)
Humans , Acne Vulgaris/diagnosis , Cicatrix , Skin , Skin Abnormalities
8.
Rev. chil. dermatol ; 31(4): 401-409, 2015. ilus
Article in Spanish | LILACS | ID: biblio-869714

ABSTRACT

El Síndrome de Ovario Poliquístico es un trastorno endocrino común que afecta a mujeres en edad reproductiva que puede causar problemas metabólicos y deterioro psicosocial importante. Las manifestaciones dermatológicas más frecuentes del hiperandrogenismo incluyen acné, hirsutismo y alopecia, cuyo reconocimiento es esencial para hacer un diagnóstico precoz. Las modalidades de tratamiento incluyen terapia hormonal con el objetivo de modular la producción de andrógenos y su acción, así como tratamientos no hormonales dirigidos a condiciones dermatológicas específicas.


Polycystic ovarian syndrome is a common endocrine disorder that affects women of reproductive age, which can cause metabolic, reproductive and psychosocial impairment. The most common skin manifestations of hyperandrogenism are acne, hirsutism and alopecia, whose recognition is essential for early diagnosis. There are several treatment modalities, including hormonal therapy in order to modulate androgen production and their effects, as well as other non hormonal treatments targeted to specific dermatologic conditions.


Subject(s)
Humans , Acne Vulgaris/diagnosis , Alopecia/diagnosis , Hirsutism/diagnosis , Polycystic Ovary Syndrome/complications , Acne Vulgaris/etiology , Acne Vulgaris/therapy , Alopecia/etiology , Alopecia/therapy , Hirsutism/etiology , Hirsutism/therapy
9.
Health sci. dis ; 16(3): 1-5, 2015. ilus
Article in French | AIM | ID: biblio-1262738

ABSTRACT

OBJECTIF : Décrire les caractéristiques épidémiologiques et cliniques de l'acné chez les adolescents scolarisés de Yaoundé. MÉTHODOLOGIE : Nous avons mené une étude transversale de Janvier à Avril 2013 au sein de 3 établissements d'enseignement secondaire de la ville de Yaoundé, Cameroun. Tout adolescent âgé de 15-19 ans et atteint d'acné était inclus dans l'étude. RÉSULTATS : Des 535 adolescents examinés, 400 (74,8%) étaient atteints d'acné, dont 214 filles (53,5%) avec un risque plus élevé chez les garçons d'être atteints (odds-ratio (OR) 1,8, intervalle de confiance (IC) à 95% : 1,2-2,7 ; p = 0,005). L'âge moyen était de 16,7 ± 1.3 ans. Les participants âgés de 16 ans étaient les plus affectés (31,7%). Le pic d'âge au début de l'acné était de 12 ans chez les filles (22,4%) et 14 ans chez les garçons (30,1%), avec significativement plus de filles affectées tôt (9-13 ans) que de garçons (14-18 ans) (OR 2,8, IC : 1,8-4,3 ; p < 0,0001). Le visage représentait le siège préférentiel (79%), et, comédons (98%) et papules (95%) étaient les types de lésions les plus nombreuses. L'acné rétentionnelle (58,5%) et l'acné polymorphe (37,5%) étaient les formes les plus rencontrées, et le grade 2 était le degré de sévérité le plus observé (41,5%). CONCLUSION : L'acné est une pathologie fréquente en milieu scolaire Camerounais. Bien que les formes sévères soient rares, les lésions semblent prédominer sur les parties exposées du corps, ce qui pourrait avoir un retentissement sur l'état psycho-affectif et la qualité de vie des patients


Subject(s)
Acne Vulgaris/diagnosis , Acne Vulgaris/epidemiology , Adolescent , Face , Schools
10.
Medicina (B.Aires) ; 74(5): 359-362, oct. 2014. tab
Article in English | LILACS | ID: lil-734401

ABSTRACT

It is well known that the reference values usually employed for endocrine biochemical measurements are those suggested by the suppliers of commercial kits despite their advice that each laboratory should set its own reference values. Our objectives were to (i) determine reference ranges for serum testosterone (T) and sex hormone binding globulin (SHBG) appropriate to our laboratory and population, and (ii) to analyze their influence on evaluating hyperandrogenemia. SHBG and T were measured, and free and bioavailable testosterone calculated, in (a) 30 selected non-hyperandrogenic women, (b) 87 non-selected healthy female blood donors, (c) 53 women with hyperandrogenism, and (d) 38 women with hyperandrogenic disorders but without biochemical hyperandrogenemia according to normal ranges suggested by the kit manufacturer. Mean serum SHBG concentrations were significantly different among all four groups. SHBG levels were significantly higher in selected normal women (group a). Using our results for this selected control group as new reference values, 12 out of 38 (31.6%) women with hyperandrogenic disorders without apparent hyperandrogenemia (group d) were recategorized as hyperandrogenemic. Similarly, 4 out of 63 (6.4%) non-selected, normal weight, women (group b), were recategorized as hyperandrogenic. Therefore, the diagnosis of hyperandrogenemia would improve accuracy by using customized reference SHBG values instead of those suggested by the suppliers.


Con frecuencia los valores de referencia utilizados para las evaluaciones bioquímicas endocrinológicas son los sugeridos por los kits utilizados, a pesar de las recomendaciones de que cada laboratorio debiera obtener sus propios valores de normalidad. Nuestros objetivos fueron (i) analizar los rangos de referencia para testosterona (T) y globulina ligadora de esteroides sexuales (SHBG) apropiados para nuestro laboratorio y población, y (ii) analizar su influencia en la evaluación de la hiperandrogenemia. Se midió T y SHBG y se calculó testosterona libre y biodisponible en un grupo (a) control de 30 mujeres no hiperandrogénicas, (b) 87 mujeres no seleccionadas donantes de sangre, (c) 53 mujeres con hiperandrogenismo, y (d) 38 mujeres con desórdenes hiperandrogénicos pero sin hiperandrogenemia de acuerdo a los rangos de normalidad sugeridos por el kit. La concentración media de SHBG fue significativamente diferente entre los cuatro grupos. Los niveles de SHBG fueron significativamente más altos en las mujeres controles seleccionadas (grupo a). Tomando en consideración los resultados obtenidos en este grupo y estableciendo los rangos de referencia adecuados, 12 de 38 mujeres (31.6%) hiperandrogénicas sin hiperandrogenemia (grupo d) fueron recategorizadas como con exceso androgénico bioquímico. De igual manera, al analizar mujeres normopesas no seleccionadas, en edad reproductiva (grupo b), 4 de 63 (6.4%) pudieron ser definidas como hiperandrogénicas. Utilizando valores adecuados de referencia para SHBG, se mejora la precisión del diagnóstico de exceso androgénico.


Subject(s)
Adult , Female , Humans , Middle Aged , Androgens/blood , Hyperandrogenism/diagnosis , Sex Hormone-Binding Globulin/analysis , Testosterone/blood , Acne Vulgaris/diagnosis , Alopecia/diagnosis , Biomarkers/blood , Dermatitis, Seborrheic/diagnosis , Hirsutism/diagnosis , Hyperandrogenism/etiology , Prospective Studies , Polycystic Ovary Syndrome/complications , Reference Values , Reagent Kits, Diagnostic/standards
11.
An. bras. dermatol ; 89(3): 428-435, May-Jun/2014. tab, graf
Article in English | LILACS | ID: lil-711610

ABSTRACT

BACKGROUND: Acne is a common disease in adolescents, but there are no epidemiological data for acne in Brazil. OBJECTIVES: To estimate the prevalence and degree of acne in adolescents from Sao Paulo and study socio-demographic factors, family history and lifestyle, associated with the disease. METHODS: Cross-sectional study with 452 adolescents aged between 10 and 17 (mean=13.3 years), students from elementary and high school, examined by 3 independent evaluators. RESULTS: 62.4% were female, 85.8% white and 6.4% were aged 14. The prevalence was 96.0% and increased with age - all students over 14 had acne. The most prevalent form of acne was comedonal (61.1%), followed by mild (30.6%) and moderate (7.6%) papular-pustular, which affected mostly the face (97.5%). About half of the adolescents reported family history for acne in mother or father, and 20.6% reported previous treatment for acne. There was a higher chance of presenting non-comedonal acne with increased age (p<0.001). DISCUSSION: The prevalence of acne in adolescents varies widely due to the clinical features and diagnostic methods used. Adolescents whose brothers/sisters had acne (OR=1.7-p=0.027) and those over 13 (OR=8.3-p<0.001), were more likely to have non-comedonal acne. CONCLUSION: This study showed high prevalence of acne in adolescents from Sao Paulo, predominantly the comedonal form on the face, with a higher chance of presenting non-comedonal acne with increased age. .


Subject(s)
Adolescent , Child , Female , Humans , Male , Acne Vulgaris/epidemiology , Age Distribution , Age Factors , Acne Vulgaris/diagnosis , Brazil/epidemiology , Cross-Sectional Studies , Educational Status , Logistic Models , Prevalence , Risk Factors , Severity of Illness Index , Sex Distribution , Sex Factors
12.
An. bras. dermatol ; 88(6): 1039-1040, Nov-Dec/2013. graf
Article in English | LILACS | ID: lil-699014

ABSTRACT

Drug-induced acne is a common skin condition whose classic symptoms can be similar to a rose pearl, as in the case of a male patient presenting with this condition after excessive use of a cream containing corticosteroids.


A acne medicamentosa é uma dermatose comum, que pode apresentar no seu quadro clássico semelhanças à pérola rosa, como no caso apresentado de um paciente do sexo masculino cujo quadro surgiu após uso intempestivo de creme contendo corticoesteróide.


Subject(s)
Humans , Male , Acne Vulgaris/chemically induced , Acne Vulgaris/diagnosis , Adrenal Cortex Hormones/adverse effects , Drug Eruptions/diagnosis , Diagnosis, Differential , Skin Cream/adverse effects
13.
Gac. méd. Caracas ; 121(3): 234-240, jul.-sept. 2013. tab
Article in Spanish | LILACS | ID: lil-731327

ABSTRACT

La isotretinoína es un retinoide empleado en el tratamiento del acné. El objetivo de este estudio fue determinar colesterol, triglicéridos, transaminasa glutámico oxalacética, transaminasa glutámico pirúvica y fosfatasa alcalina, pretratamiento, trimestralmente durante el tratamiento y postratamiento en pacientes tratados con isotretinoína oral procedentes de consultas dermatológicas del Estado Carabobo. La edad Promedio de la muestra estudiada fue (19,4 ± 4,7 años), los valores de colesterol mostraron variación estadísticamente significativa para el primer trimestre (P=0,044), Los triglicéridos se incrementaron en el segundo trimestre (P=0,036) para ambos géneros, mientras que para el tercer trimestre solo el género masculino experimentó incremento. Transaminasa glutámico oxalacético en el primer trimestre se incrementó en el género femenino, sin embargo, no fue estadísticamente significativo. En los demás trimetres los valores de las enzimas hepáticas no superaron los valores de referencia. No se evidencian diferencias estadísticamente significativas entre los niveles del pretratamiento y postratamiento. Es recomendable monitorear los lípidos séricos y transaminasas durante el primer trimestre de tratamiento aunque los cambios observados fueron discretos en la mayoría de los pacientes


Isotretinoin is a retinoid used to treat acne. The aim of this sindy was to determine cholesterol, triglyceride, seric glutami oxalacetic transaminase, seric glutami pyruvic transaminase and alkaline phosphatase pretreatment, quarterly during treatment and post-treatment in patients treated with oral isotretinoin dermatological consultations from Carabobo State. The overage age of the sample was (19.4 ± 4.7 years), cholesterol values showed statistically significant variation in the first quarter (P=0.044). Triglycerides increased in the second quarter (P=0.036) for both genders, while for the third quarter only increase in male. Seric glutami oxalacetic transaminase in the first quarter increased in females, but was not statistically significant. In other quarters the liver enzyme values did not exceed reference values. No statistically significant differences are evident between the levels of pretreatment and postreatment. It is advisable to monitor serum lipids and transaminases during the first quarter of treatment although the observed changes were discrete in most patients


Subject(s)
Humans , Male , Adolescent , Female , Acne Vulgaris/diagnosis , Acne Vulgaris/therapy , Cholesterol/blood , Dermatologic Agents/administration & dosage , Isotretinoin/therapeutic use , Retinoids/adverse effects , Triglycerides/blood , Aspartate Aminotransferases/analysis , Keratolytic Agents/administration & dosage , Sebaceous Glands , Transaminases/analysis
14.
S. Afr. fam. pract. (2004, Online) ; 55(3): 241-244, 2013.
Article in English | AIM | ID: biblio-1270026

ABSTRACT

Acne is a chronic inflammatory disease of the pilosebaceous units. It is the most common diagnosis in dermatology and regularly affects adolescents and young adults. Acne can be mild; moderate or severe. Treatment includes topical keratolytics; topical retinoids; antibiotics; hormonal therapy and systemic retinoids in severe cases


Subject(s)
Acne Vulgaris/diagnosis , Adolescent , Patient Care Management , Young Adult
15.
Rev. méd. Chile ; 140(5): 637-639, mayo 2012. ilus
Article in Spanish | LILACS | ID: lil-648592

ABSTRACT

Background: Rosacea fulminans is a rare condition, characterized by a sudden onset of papulopustules, cysts, edema, and draining sinuses usually confined to the facial area. It is often accompanied by low-grade fever, myalgias and leukocytosis. Patients usually have a background of mild rosacea. We report two male patients aged 29 and 54 years, presenting with rosacea fulminans and ocular involvement, triggered by the use of topical steroids. Both responded to systemic treatment with corticosteroids, isotretinoin and metronidazole. Rosacea fulminans should be considered as a variant of rosacea that includes papulopustular, ocular, phymatous and erythematotelangiectatic types.


Subject(s)
Adult , Humans , Male , Middle Aged , Adrenal Cortex Hormones/adverse effects , Eye Diseases/chemically induced , Facial Dermatoses/chemically induced , Rosacea/chemically induced , Acne Vulgaris/diagnosis , Diagnosis, Differential , Facial Dermatoses/drug therapy , Rosacea/drug therapy
17.
An. bras. dermatol ; 86(6): 1113-1121, nov.-dez. 2011. tab
Article in English | LILACS | ID: lil-610415

ABSTRACT

BACKGROUNDS: Skin diseases are extremely frequent and may affect quality of life; therefore, it is important to assess it and identify which factors are associated with it. OBJECTIVES: To assess quality of life and its associated factors in dermatological patients. METHODS: A cross-sectional study involving a sample of 548 patients seen at the Dermatology Outpatient Clinic of Sistema Único de Saúde (the Brazilian National Public Health System), University Hospital, Federal University of Rio Grande do Sul (RS). Information related to socio-demographic data, medical consultation and quality of life was collected by means of the Dermatology Life Quality Index. RESULTS: A median of 7 and a mean of 7.7 (SD = 5.0) were obtained with the Dermatology Life Quality Index. The skin diseases with higher scores on the Dermatology Life Quality Index were psoriasis (median = 15.5), vitiligo (median = 13), atopic dermatitis (median = 12) and acne (median = 10). With respect to factors associated with quality of life, it was found that younger, single patients with a low income, one skin disease and longer disease duration presented poorer quality of life. CONCLUSION: The assessment of the impact of dermatoses on patients' quality of life is important for clinical management. It is essential to detect patients at higher risk of experiencing worse quality of life in order to treat them in a more integrated way.


FUNDAMENTOS: As doenças de pele são extremamente freqüentes e os pacientes podem ter a qualidade de vida afetada. Assim é importante medi-la, bem como verificar quais os fatores que podem estar associados. OBJETIVOS: Verificar a qualidade de vida em pacientes dermatológicos e os fatores associados. MÉTODOS: Estudo tranversal com uma amostra de 548 pacientes atendidos no ambulatório de dermatologia do Sistema Único de Saúde do Hospital Universitário da Universidade Federal do Rio Grande. As informações foram coletadas em um questionário pré-codificado e referiam-se à dados sócio-demográficos, da consulta e qualidade de vida. RESULTADOS: O escore total do Dermatology Life Quality Index foi uma mediana de 7 e uma média de 7,7 (DP=5,0). As dermatoses com escore maior no Dermatology Life Quality Index foram psoríase (mediana = 15,5), vitiligo (mediana =13), dermatite atópica (mediana = 12), acne (mediana=10). Com respeito aos fatores associados à qualidade de vida, identificou-se que pacientes mais jovens, com menor renda, solteiros, com uma dermatose e com um tempo maior de evolução da doença, apresentam pior qualidade de vida. CONCLUSÃO: A avaliação do impacto na qualidade de vida em pacientes com dermatoses é importante para o manejo clínico. É essencial a detecção daqueles pacientes com maior risco de apresentar uma qualidade de vida pior, para poder abordá-los de uma forma mais integrada.


Subject(s)
Adolescent , Adult , Aged , Female , Humans , Male , Middle Aged , Young Adult , Quality of Life/psychology , Skin Diseases/diagnosis , Acne Vulgaris/diagnosis , Brazil/epidemiology , Cross-Sectional Studies , Dermatitis, Atopic/diagnosis , Psoriasis/diagnosis , Socioeconomic Factors , Surveys and Questionnaires , Skin Diseases/epidemiology , Skin Diseases/psychology , Vitiligo/diagnosis
18.
Pediatr. mod ; 47(2)mar.-abr. 2011.
Article in Portuguese | LILACS | ID: lil-590920

ABSTRACT

A acne juvenil é a doença dermatológica mais comum na adolescência, sendo considerada doença crônica, de caráter inflamatório, que acomete a estrutura pilossebácea. Pelas graves repercussões psicossociais que pode determinar no adolescente, não mais se admite seu entendimento como doença trivial e passageira e, portanto, não se justifica postergar o tratamento, submetendo o jovem ao risco de cicatrizes indeléveis. Aderência ao tratamento é o ponto chave na condução clínica do paciente e o abandono é o principal motivo de falha do tratamento. Neste artigo são revisados os conceitos sobre a etiopatogenia, apresentação clínica e aspectos terapêuticos da acne.


Subject(s)
Humans , Male , Female , Adolescent , Acne Vulgaris/diagnosis , Acne Vulgaris/etiology , Acne Vulgaris/therapy , Adolescent Health
19.
An. bras. dermatol ; 85(6): 789-795, nov.-dez. 2010. graf, tab
Article in Portuguese | LILACS | ID: lil-573616

ABSTRACT

FUNDAMENTOS: A acne da mulher adulta (AMA) é uma dermatose de incidência crescente; o hiperandrogenismo está presente em muitos casos, mas há pacientes sem anormalidades hormonais. OBJETIVO: Analisar as características prevalentes na mulher adulta com acne sem hiperandrogenismo. MATERIAL E MÉTODO: Um levantamento de 226 prontuários com queixa de AMA foi realizado; 116 pacientes (51,3 por cento) possuíam perfil hormonal normal e, portanto, foram incluídas no estudo. Foram pesquisados idade, etnia, perfil clínico da acne, exames complementares, tratamentos anteriores, tratamentos prescritos e evolução. RESULTADOS: A média das idades foi de 33,9 anos e o grau clínico predominante foi o inflamatório moderado (grau II); a face foi a área mais acometida. Os retinoides tópicos foram as drogas mais prescritas, e a medicação sistêmica foi indicada em 53,4 por cento das pacientes. A regressão total foi observada em 31 pacientes (26,7 por cento) até 12 semanas de tratamento. Houve reação adversa ao tratamento tópico em 21,5 por cento das pacientes. CONCLUSÃO: O quadro clínico da AMA em pacientes sem hiperandrogenismo é de moderada intensidade, com predomínio de lesões inflamatórias. Seu tratamento é similar ao da acne vulgar; entretanto, atenção especial deve ser tomada com medicações de maior potencial irritante, uma vez que esse grupo parece ter uma maior predisposição a irritações cutâneas.


BACKGROUND: Adult female acne (AFA) is a dermatosis of increasing incidence; hyperandrogenism is present in many cases, but there are patients without hormonal abnormalities. OBJECTIVE: To analyze the prevalent characteristics in adult women with acne without hyperandrogenism. MATERIAL AND METHODS: A survey of 226 medical records with AFA complaints was conducted; of these, 116 (51.3 percent) had a normal hormonal profile and were, therefore, included in the study. We investigated age, ethnicity, clinical profile of acne, complementary exams, previous treatment, prescribed treatment and evolution. RESULTS: The mean age was 33.9 years and the predominant clinical grade of acne was moderate inflammatory (grade 2). The face was the most affected area. Topical retinoids were the most prescribed drugs, and systemic medication was prescribed to 53.4 percent of the patients. Total regression was observed in 31 patients (26.7 percent) within 12 weeks of treatment. Adverse reactions to topical treatment occurred in 21.5 percent of the patients. CONCLUSION: The clinical manifestations of AFA in patients without hyperandrogenism are moderate, with predominance of inflammatory lesions. Treatment is similar to that of acne vulgaris; however, special attention should be taken with more irritating medication since this group appears to be more predisposed to skin irritations.


Subject(s)
Adult , Female , Humans , Acne Vulgaris/epidemiology , Acne Vulgaris/diagnosis , Acne Vulgaris/drug therapy , Acne Vulgaris/etiology , Brazil/epidemiology , Follow-Up Studies , Retrospective Studies , Severity of Illness Index
20.
An. bras. dermatol ; 84(4): 349-354, jul.-ago. 2009. graf, tab
Article in Portuguese | LILACS | ID: lil-529079

ABSTRACT

FUNDAMENTOS: Acne é dermatose comum que acomete ambos os gêneros e todas as faixas etárias. Mulheres apresentam diferentes padrões clínicos da doença, além de frequente persistência da acne após a adolescência. OBJETIVO: Analisar características clínicas e epidemiológicas associadas às diferentes faixas etárias acometidas por acne feminina. MÉTODOS: Estudo transversal envolvendo mulheres com diagnóstico de acne, atendidas em ambulatório de dermatologia geral. Variáveis relacionadas à doença e às pacientes foram avaliadas com o emprego de questionário padronizado. RESULTADOS: Avaliaram-se 103 pacientes, cuja idade média na época da consulta foi 21,7 ± 7,3 anos. Definiram-se dois subgrupos com idade de corte de 21 anos e idades médias de 15,8 ± 2,3 e 28,0 ± 5,1 anos. Houve correlação entre a duração do quadro e a idade das pacientes na consulta (R = 0,7). Observaram-se diferenças entre os grupos nas frequências de uso de contraceptivo oral combinado (OR = 48,1), lesões no colo (OR = 11,6), lesões no dorso (OR = 0,2), predominância na topografia superior da face (OR = 0,1) e idade de início das lesões (OR = 1,8). No grupo de mulheres adultas, 80 por cento relataram início do quadro antes dos 20 anos. CONCLUSÕES: Identificaram-se padrões clínicos cronológicos e topográficos que caracterizaram a acne feminina em diferentes faixas etárias, alertando para a importância da abordagem diagnóstica e terapêutica individualizada.


BACKGROUND: Acne is a frequent skin disease that occurs in both sexes and all age-groups. Women present several clinical disease patterns; moreover, persistence after adolescence is common. OBJECTIVE: To analyze clinical and epidemiological characteristics associated with different age-groups affected by acne in women. METHODS: Cross-sectional study involving female patients diagnosed with acne, at a general dermatology outpatient clinic. Variables related to disease and patients were assessed through a standardized questionnaire. RESULTS: One hundred and three women were assessed. The average age of patients at the time of the consultation was 21.7 ± 7.3 years. Two groups were defined (cut-off age of 21 years), with means of 15.8 ± 2.3 and 28.0 ± 5.1 years. There was correlation between disease duration and current age (R=0.7). There were group differences among frequencies of covariables: combined oral contraceptive (OR=48.1), lesions located on upper chest (OR=11.6), lesions on upper dorsum (OR=0.2), predominance on upper half of face (OR=0.1) and age at disease onset (OR=1.8). Among adult women, 80 percent reported acne onset before 20 years of age. CONCLUSION: Chronologic and topographic patterns of female acne in different age-groups were defined, reinforcing the importance of an individualized diagnostic and therapeutic approach.


Subject(s)
Adolescent , Adult , Female , Humans , Young Adult , Acne Vulgaris/diagnosis , Acne Vulgaris/epidemiology , Age Distribution , Cross-Sectional Studies , Young Adult
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